Infantile Fibrosarcoma

This is a below knee amputation specimen from the left lower limb of a 3 year old male. The swelling was on the plantar aspect of the left foot and extending to the medial surface. The lesion was apparently present since early infancy (since birth??). The initial...

Retinoblastoma – effect of digital editing

Gross picture of the cut surface of the eyeball from a case of retinoblastoma in a 3 and a half year old female. This set of two pictures highlights the advantages and disadvantages of digitally editing photos. The original picture has a poorly contrasted background...

Cleft Lip & Polydactyly

Male fetus, of consanguineous marriage; 21 weeks gestational age. The fetus had cleft lip and polydactyly of bilateral hands and feet.      ...

Thymolypoma

This 27 year old woman had breathlessness and chest pain since 3 years and an examination revealed only diminished breath sounds. CT scan diagnosis was "Lipomatosis". Per op: a 'dumbbell' shaped fatty tumor was seen in the mediastinum that almost completely compressed...

Gene Expression – A promising alternative to IHC?

Traditionally, the pathologist has relied on immunohistochemistry (IHC) to arrive at a conclusion when confronted with cancers of unknown primary or undifferrentiated malignancies. A relatively recent development is, however threatening to upstage this current...

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